• A richly illustrated reference on immune-mediated diseases in dogs and cats, grounded in veterinary clinical practice

    Veterinary Clinical Immunology provides clear and accurate information on the pathogenesis, diagnosis, and treatment of immune-mediated diseases in small animals. Written by practicing clinicians for practicing clinicians, this highly practical resource contains user-friendly chapters on general and specific testing methods, common and atypical immune-mediated diseases, vaccinationbest practice and controversies, and more.

    Divided into four sections, the textbook opens with a thorough immunology primer for clinicians, describing innate and adaptive immunity, pathophysiology, immunogenetics, and pathogens. Subsequent sections focus on diagnostic approaches and treatments, immunodeficiency and onco-immunology, and a range ofspecific immune-mediated diseases, including diseases of the hematopoietic system, the oral cavity and gastrointestinal tract, the kidneys and bladder, and the nervous and endocrine systems.

    • Provides information directly applicable to clinical practice with emphasis on the diagnosis and management of immunological conditions
    • Features numerous real-world case examples supported by high-quality images of blood smears, tissue sections, and other specimens relevant to the clinical pathology of immune-mediated diseases
    • Includes access to a companion website with video clips of clinical cases and additional teaching resources
    • Authored and edited by internationally-recognized experts in their respective fields

    Veterinary Clinical Immunology is a must-have for busy primary practitioners and specialists looking for a current and comprehensive reference source. It is also a valuable clinically-based textbook for undergraduate and postgraduate veterinary students, trainees, residents, and veterinary technicians and nurses.

  • List of Contributors vii

    Preface x

    About the Companion Website xi

    Section 1 A Primer for the Clinician 1

    1 A Clinician’s Guide to the Immune System: Innate and Adaptive Immunity 3
    Oliver A Garden

    2 Pathophysiology of Immune- Mediated Disease 39
    James W Swann

    3 Immunogenetics: The Final Frontier 61
    Lucy Davison and Lorna J Kennedy

    4 Vector- Borne Pathogens and Immune- Mediated Disease 84
    Linda Kidd and Edward B Breitschwerdt

    Section 2 Diagnostic Approaches and Treatment 107

    5 Diagnosing Immune- Mediated Disease: General Approach and Specific Tests 109
    Linda Kidd and Amy L MacNeill

    6 Treating Immune- Mediated Disease: What to Use and When 134
    Todd M Archer and Claire L Fellman

    Section 3 Specific Immune- Mediated Diseases 165

    7 Blood and Hematopoietic System 167
    Todd M Archer

    8 Musculoskeletal System 192
    Karen Perry

    9 Central and Peripheral Nervous System 234
    Nicolas Granger and Linda Kidd

    10 Urinary Tract 279
    Jack S Lawson and Harriet M Syme

    11 Oral Cavity and Gastrointestinal Tract 313
    Karin Allenspach, Al Jergens, Laura van Vertloo, and Brenda Mulherin

    12 Liver, Biliary Tract, and Exocrine Pancreas 347
    Penny Watson, Nick Bexfield, and Michael J Day

    13 Nose, Trachea, and Bronchopulmonary System 387
    Leah A Cohn, Cécile Clercx, and Michael J Day

    14 Endocrine Organs 421
    Lucy J Davison

    15 Skin 436
    Domenico Santoro

    16 Eye and Adnexa 469
    Màrian Matas Riera and Oliver A Garden

    17 Polysystemic Autoinflammatory and Autoimmune Diseases 503
    Jonathan E Fogle

    Section 4 Immunodeficiency, Onco-Immunology, and Vaccination 521

    18 Primary Immunodeficiencies 523
    James W Swann

    19 Cancer Immunology 549
    David Killick

    20 Vaccination 580
    Alison Stickney and NJ Cave

    Index 615

  • Oliver A. Garden, Dean of the School of Veterinary Medicine and the Kenneth Burns Endowed Chair in Veterinary Medicine at Louisiana State University, USA.

    Linda Kidd, DVM, PhD (Immunology), DACVIM (SAIM), Western University of Health Sciences, California, USA.

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