Studies on Veterinary Medicine
De: Lester Mandelker, Peter Vajdovich
ISBN: 9781617790706
2011, Springer
Capa dura
Páginas: 251
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- Presents cutting-edge research in an accessible manner
- Features contributions by leading scientists in the field
- Comprehensively reviews the subject matter
This compendium of research material on the role of oxidative stress in animal disease and morbidity examines both the general and the specific. Sourced from scientists, veterinarians, and members of the medical community from around the world, it includes chapters on our wider understanding of the corrosive function of free radicals in cell biology as well as focusing on the interplay between oxidative stress and metabolism in a variety of animal species including dogs, ruminants and birds.
Since biogerontologist Denham Harman first posited that free radicals arising from the metabolic activity of oxygen play a central role in aging and disease, a mass of evidence has accumulated linking oxidative stress and biological degradation. We now understand that living in an aerobic environment inevitably leads to the production of free radicals that go on to attack biological membranes and lipoproteins via oxidation in a process called lipid peroxidation. Reacting with carbon-based molecules such as polyunsaturated fatty acids, these free radicals cause oxidative stress and tissue damage.
The purpose of Studies on Veterinary Medicine is to inform clinicians, students and others of the plethora of consequences that free radical damage (ROS) has on various cells, tissues, and organs, as well as in different species of animals. The chapters also analyze the effects of oxidative stress on aging and various morbidities such as diabetes, cognitive dysfunction and heart disease. Contributors variously present their interpretation of the role played by oxidative damage in disease and assess the benefits of antioxidant therapies.
- Oxidative Stress, Free Radicals, and Cellular Damage
Pages 1-17
Mandelker, Lester
- Use of Free Radicals and Antioxidants in Inflammatory Processes of Animals
Pages 19-50
Vajdovich, Peter
- Oxidative Stress and Calcium Metabolism
Pages 51-59
Schenck, Patricia A.
- TRPM2 Cation Channels and Oxidative Stress-Induced Neuronal Cell Death
Pages 61-76
Naziroğlu, Mustafa
- Oxidative Stress in Diabetes Mellitus
Pages 77-91
Comazzi, Stefano
- Oxidative Stress in the Spinal Cord of Dogs and Cats
Pages 93-100
Baltzer, Wendy
- Oxidative Stress, Cognitive Dysfunction, and Brain Aging
Pages 101-111
Head, Elizabeth (et al.)
- The Role of Oxidative Stress in Ocular Disease
Pages 113-131
Zapata, Gustavo L.
- Oxidative Stress in Heart Failure
Pages 133-152
Moe, Gordon
- Nutrient Selection in the Management of Canine Atopic Dermatitis
Pages 153-160
Kuck, John
- Avian Antioxidants and Oxidative Stress: Highlights from Studies of Food, Physiology, and Feathers
Pages 161-174
McGraw, Kevin J.
- Free Radicals and Antioxidants in Avian Diseases
Pages 175-190
Mézes, Miklós (et al.)
- Oxidative Stress in Ruminants
Pages 191-231
Celi, Pietro
- Antioxidant and Anti-inflammatory Effects of Common Pharmaceuticals and Nutraceuticals
Pages 233-251
Mandelker, Lester (et al.)
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Dr. Lester Mandelker
Is a private veterinary practitioner at Community Veterinary Hospital in Largo, Florida. He has been the Owner/Director of this AAHA certified animal hospital since 1972.
He is a diplomate of the American Board of Veterinary Practitioners and has developed a special interest in practice pharmacology, antioxidants and nutraceuticals. He has appeared on ABC news on the use of Pet Supplements and Antioxidants. Check out the eVideo. eVideo: Medical: Pet Supplements.
Dr. Mandelker is the only board certified veterinarian for both canine and feline medicine in Pinellas County.
Dr. Mandelker is also the pharmacology editor and consultant for the Veterinary Information Network (VIN*) and is on the advisory board of Veterinary Forum Magazine and writes a monthly column on pharmacology. He has written over 150 scientific articles for publication in such journals as the AVMA, VM/SAC, Canine Practice and Veterinary Forum. He is the editor of book "Nutraceuticals and Other Biological Therapies" pulbished by The Veterinary Clinics of North America, January 2004. He has co-authored two books on practice tips and has written numerous articles on avian anesthesia. He lectures on practice tips and pharmacology at various state and local meetings and is available for seminars.
Editor "Veterinary Clinics of North America Jan 2008
"Oxidative Stress: The Role of Mitochondria, Free Radicals and Antioxidants."A/Prof Peter Vajdovich
PVM, PhD, Dipl. ECVCP
EBVS® European Specialist in Veterinary Clinical Pathology
Member of European College of Veterinary Clinical Pathology
Peter Vajdovich DVM PhD, Dipl. ECVCP. He qualified as a veterinary surgeon in 1990. Since then he has been working at the Faculty of Veterinary Science, Budapest, Hungary. He started his work with clinical pathology, clinical cytology, and he became a pioneer of clinical oncology in Hungary. He defended his PhD theses in 2000, about the topic of ``Free radical and antioxidant parameters in red blood cells (examination in cattle, dogs and rats)``. He became a college member of the European College of Veterinary Clinical Pathology (ECVCP) in 2003. Then he partly turned to Clinical Oncology, and he became a member of the European Society of Veterinary Oncology (ESVONC) in 2004. He opened a private oncology and haematology clinic for small animals in 2009. Since then he has followed his clinical, laboratory and research aims there. In 2014 he was pointed out as a head of a newly organized department, Department of Clinical Pathology and Oncology at the Veterinary Faculty. This year he became the head of the Credential Committee in ECVCP and a member of the Scientific Committee in ESVONC. He is author of several research articles written in the field of veterinary clinical pathology and oncology. He is doing routine laboratory and clinical oncology work, he is involved in graduate and postgraduate education in the Faculty and he is pursuing his research interests in veterinary laboratory development (coagulation, free radicals and antioxidants, flow cytometry) and clinical oncology (multidrug resistance, local chemotherapy) of companion and partly farm animals. He is a father of four children and a husband of a veterinary dermatologist wife.