• Greene's Infectious Diseases of the Dog and Cat, 5th Edition provides a comprehensive, clinically useful reference on the management of infectious diseases caused by viruses, bacteria (including rickettsiae, chlamydiae, mycoplasmas, and spirochetes), fungi, algae, protozoa, parasites, and other atypical agents. Each section guides the reader through diagnostic testing for specific infectious diseases, from specimen collection to laboratory submission to interpretation of results to appropriate treatment measures. Full-color illustrations and hundreds of tables provide convenient access to diagnostic and therapeutic recommendations, along with the appropriate drug dosages for effective treatment and prevention. A fully searchable enhanced eBook version is included with print purchase, allowing access to all of the text and figures on a variety of digital devices.

    New to this edition

    • NEW! Improved format includes overarching information on diagnosis, treatment, and prevention in the first part of the book, followed by specific pathogens and clinical problems in the second and third parts of the book, respectively.
    • NEW! Parasite section includes coverage of disease caused by nematodes, (including heartworm disease), cestodes, trematodes, mites, ticks, fleas, and biting flies.
    • NEW! Renewed focus on clinical relevance is applied throughout the text.
    • NEW! Updated clinical images, maps, and life-cycle drawings are included in every chapter.
    • NEW! Expanded sections on public health for each pathogen emphasize the One Health approach, promoting the interrelationship of human, animal, and environmental health.
    • NEW! Information on SARS-CoV-2 relates its importance and relevance to animal health.
    • NEW! Updated information on vaccination recommendations for client-owned and shelter animals is included as an Appendix.

    Key Features

    • More than 150 internationally recognized experts contribute chapters on topics in their field of specialty.
    • Clear and logical organization of chapters provides a solid basis for an approach to diseases caused by specific pathogens, with the first part of the book including sections on diagnostic approaches, treatments (including recommended antimicrobial drug doses), and prevention.
    • Specific pathogens are addressed in the second part of the book, using a structured approach that includes etiology/epidemiology (relevance to wildlife animal hosts, role of the environment), clinical and laboratory findings, treatment, prevention, and public health implications.
    • Case examples illustrate principles and highlight how the material can be applied.
    • More than 800 clinical images, maps, life cycles, and photomicrographs assist with accurate understanding of epidemiology, pathogenesis, diagnosis of disease, and disease prevention.
    • Visually appealing maps and life-cycle drawings enhance your comprehension and retention of the material.
    • Convenient drug dosage tables in each chapter provide complete prescribing information; chapters on antimicrobial drugs in the first part of the book summarize pharmacokinetics, indications, contraindications, handling and administration guidelines; and dosage recommendations are made for antivirals, antibacterials, antifungals, antiprotozoals, and antiparasitic drugs. The book emphasizes approaches to optimize antimicrobial stewardship.
    • Clinical Problems section helps you understand what infectious diseases should be considered in animals seen with clinical signs relating to different organ systems.
    • Suggested readings and references are listed in each chapter, facilitating further research and study.
    • Fully searchable enhanced eBook version is included with print purchase, allowing access to all of the text and figures on a variety of digital devices.
  • Section I: Viral, Rickettsial, Chlamydial, and Mycoplasmal Diseases

    1. Laboratory Diagnosis of Viral and Rickettsial Infections and Epidemiology of Infectious Disease

    2. Antiviral and Immunodulatory Chemotherapy

    3. Canine Distemper

    4. Infectious Canine Hepatitis and Canine Acidophil Cell Hepatitis

    5. Canine Herpesvirus Infection

    6. Canine Infectious Tracheobronchitis

    7. Nonrespiratory Parainfluenza Virus Infection of Dogs

    8. Canine Viral Enteritis

    9. Canine Viral Papillomatosis

    10. Feline Parvoviral Infections

    11. Feline Coronavirus Infections

    12. Feline Enteric Infections

    13. Feline Leukemia Virus Infection

    14. Feline Immunodeficiency Virus Infection

    15. Feline Adenovirus Infection

    16. Feline Respiratory Disease

    17. Feline Foamy (Syncytium-Forming) Virus Infection

    18. Feline Paramyxovirus Infections

    19. Poxvirus Infection

    20. Feline Viral Papillomatosis

    21. Miscellaneous Viral Infections

    22. Rabies and Other Lyssavirus Infections

    23. Pseudorabies

    24. Enterovirus Infections

    25. Mumps and Influenza Virus Infections

    26. Arthropod-Borne Viral Infections

    27. Salmon Poisoning Disease

    28. Ehrlichiosis, Neorickettsiosis, Anaplasmosis, and Wolbachia Infection

    29. Rocky Mountain Spotted Fever, Murine Typhus-Like Disease, Rickettsialpox,Typhus, and Q Fever

    30. Chlamydial Infections

    31. Hemotropic Mycoplasmosis (Haemobaronella)

    32. Mycoplasmal, Ureaplasmal and L-Form Infections

    Section II: Bacterial Diseases

    33. Laboratory Diagnosis of Bacterial Infections

    34. Antibacterial Chemotherapy

    35. Streptococcal and Other Gram-Positive Bacterial Infections

    36. Staphylococcal Infections

    37. Gram-Negative Bacterial Infections

    38. Endotoxemia

    39. Enteric Bacterial Infections

    40. Canine Brucellosis

    41. Anaerobic Infections

    42. Botulism

    43. Tetanus

    44. Leptospirosis

    45. Borreliosis

    46. Miscellaneous Bacterial Infections

    47. Plague

    48. Tularemia

    49. Actinomycosis and Nocardiosis

    50. Mycobacterial Infections

    51. Dermatophilosis

    52. Abscesses and Pyogranulomatons Inflammation Caused by Bacteria

    53. Bite Wound Infections

    54. Bartonellosis

    55. Surgical and Traumatic Wound Infections

    Section III: Fungal Diseases

    56. Laboratory Diagnosis of Fungal and Algal Infections

    57. Antifungal Chemotherapy

    58. Cutaneous Fungal Infections

    59. Blastomycosis

    60. Histoplasmosis

    61. Cryptococcosis

    62. Coccidioidomycosis

    63. Sporotrichosis

    64. Aspergillosis and Penicilliosis

    65. Candidiasis and Rhodotorulosis

    66. Trichosporonosis

    67. Miscellaneous Fungal Infections

    68. Pneumoystosis

    69. Protothecosis

    Section IV: Protozoal Diseases

    70. Laboratory Diagnosis of Protozoal Infections

    71. Antiprotozoal Chemotherapy

    72. Trypanosomiasis

    73. Leishmaniasis

    74. Hepatozoonosis

    75. Microsporidiosis

    76. Cytauxzoonosis

    77. Babesiosis

    78. Enteric Protozoal Infections

    79. Acanthamebiasis and Hartmannelliasis

    80. Toxoplasmosis and Neosporosis

    81. Enteric Coccidiosis

    82. Cryptosporidiosis and Cyclosporiasis

    83. Rhinosporidiosis

    84. Neurologic Diseases of Suspected Infectious Origin

    Section V: Clinical Problems

    85. Integumentary Infections

    86. Musculoskeletal Infections

    87. Cardiovascular Infections

    88. Respiratory Infections

    89. Gastrointestinal and Intra-Abdominal Infections

    90. Hepatobiliary Infections

    91. Genitourinary Infections

    92. Ocular Infections

    93. Central Nervous System Infections

    94. Environmental Factors in Infectious Disease

    95. Immunodeficiencies and Infectious Diseases

    96. Fever

    97. Prevention and Management of Infectious Diseases in Multiple-Cat Environments

    98. Prevention and Management of Infection in Kennels

    99. Immunocompromised People and Pets

    100. Immunoprophylaxis and Immunotherapy


    1. Canine Immunization Recommendations

    2. Feline Immunization Recommendations

    3. Canine and Feline Biologics Manufacturers and Products Available Worldwide

    4. Compendium of Animal Rabies Vaccines

    5. Laboratory Testing for Infectious Diseases of Dogs and Cats

    6. Manufacturers of Diagnostic Test Kits and Their Products

    7. Infectious Disease Rule-Outs for Medical Problems

    8. Antimicrobial Drug Formulary

  • Jane E. Sykes

    BVSc(Hons), PhD, DACVIM, Director, Small Animal Clinic; William R. Pritchard Veterinary Medical Teaching Hospital and Professor; Department of Medicine and Epidemiology; University of California; Davis, California