• In this issue, guest editors bring their considerable expertise to this important topic.


    Key Features

    Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

    • Cover image

    • Title page

    • Table of Contents

    • Copyright

    • Contributors

    • Forthcoming Issues

    • Preface

    • Relevant Equine Renal Anatomy, Physiology, and Mechanisms of Acute Kidney Injury: A Review

    • Key findings

    • Introduction

    • Equine renal anatomy

    • Renal blood flow

    • Glomerular filtration and autoregulation of glomerular blood flow

    • Mechanisms of acute kidney injury

    • Tubular ischemia

    • Toxic tubular necrosis and apoptosis

    • Nonsteroidal antiinflammatory drug nephrotoxicity

    • Hemodynamically mediated or sepsis-associated nephropathy

    • Pigment nephropathy

    • Acute interstitial nephritis

    • Obstructive nephropathy

    • Acute Kidney Injury and Renal Failure in Horses

    • Key points

    • Introduction

    • Causes of acute renal failure

    • Clinical signs

    • Diagnosis

    • Treatment of acute renal failure

    • Prognosis of acute renal failure

    • Prevention of acute kidney injury and renal failure

    • Summary

    • Chronic Renal Failure-Causes, Clinical Findings, Treatments and Prognosis

    • Key points

    • Chronic kidney disease and chronic renal failure-terminology

    • Prevalence

    • Diagnosis: clinical findings

    • Diagnosis: laboratory findings

    • Diagnosis: staging

    • Diagnosis: other complementary examinations

    • Pathogenesis: acute and chronic kidney disease are interlinked

    • Causes of chronic kidney disease

    • Therapeutic options

    • Urinary Tract Disorders of Foals

    • Key points

    • Introduction

    • Clinical evaluation of the urinary system in foals

    • Acute kidney injury and acute renal failure

    • Patent urachus

    • Uroperitoneum

    • Hydroureter syndrome

    • Congenital urinary disorders

    • Discolored Urine in Horses and Foals

    • Key points

    • Introduction

    • Discussion

    • Summary

    • Urinary Incontinence and Urinary Tract Infections

    • Key points

    • Congenital diseases

    • Ectopic ureter

    • Evaluation of urinary incontinence in adult horses

    • Neurologic control of micturition

    • Clinical signs of neurologic bladder dysfunction

    • Neurologic causes of urinary incontinence

    • Idiopathic bladder paralysis

    • Trauma: damage to the urethral sphincter

    • Cystitis and urethritis

    • Estrogen-responsive urinary incontinence

    • Polyuria

    • Toxicities

    • Polyuria and Polydipsia in Horses

    • Key points

    • Introduction

    • Thirst, water consumption, and urine production in normal horses

    • Polyuria caused by chronic renal failure

    • Postobstructive disease

    • Diabetes insipidus

    • Diabetes mellitus

    • Cushing disease

    • Fluid therapy as a cause of polyuria

    • Other causes of polyuria

    • Psychogenic polydipsia

    • Disclosure

    • Metabolic Disorders Associated with Renal Disease in Horses

    • Key points

    • Introduction

    • Discussion

    • Summary

    • Imaging of the Urinary Tract

    • Key points

    • Introduction

    • Endoscopy

    • Ultrasonography

    • Radiography

    • Computed tomography

    • Nuclear scintigraphy

    • Summary

    • Disclosure

    • Supplementary data

    • Surgery of the Equine Urinary Tract

    • Key points

    • Surgery for urolithiasis

    • Ectopic ureter

    • Nephrectomy

    • Surgery of the urethra

    • Disclosure

  • Thomas J. Divers

    Earned his DVM from the University of Georgia and completed an internship in large animal medicine at the University of California at Davis. Dr. Divers returned to the University of Georgia for a residency in large animal internal medicine and ambulatory practice and later worked for 2 years as an assistant professor in the large animal medicine and ambulatory practice at the college. Dr. Divers then moved to the University of Pennsylvania for 10 years, where he was an associate professor of large animal medicine and served as chief of the section of medicine at the New Bolton Center of the University of Pennsylvania. Currently Dr. Divers is Professor of Medicine and co-Chief of the Section of Large Animal Medicine at Cornell University. He has been the recipient of teaching awards at three universities, has received the Educator of the Year Award from both the AAEP and ACVECC and recently received the Cornell University Hospital for Animals Distinguished Service Award for service to referring veterinarians. He is a diplomate of both the American College of Veterinary Internal Medicine and of the American College of Veterinary Emergency and Critical Care. He is co-author of three textbooks, has authored numerous book chapters, and has more than 190 peer-reviewed scientific publications. Dr. Divers is currently consulting editor of Veterinary Clinics of North America-Equine Practice. Dr. Divers’ current research focuses on newly discovered hepatitis viruses in horses. Other research activities have included bacterial and toxic causes of liver failure in horses, equine neurological diseases including equine motor neuron disease and equine protozoal myelitis, equine lyme disease, equine leptospirosis, diseases of the urinary system, and advances in internal medicine and critical care for horses, foals, and dairy cattle

    Affiliations and expertise

    Professor, Large Animal Medicine,Department of Clinical Studies,Cornell University,Ithaca, New York

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