Medicina Interna Gastroenterologia

Canine Hepatobiliary and Exocrine Pancreatic Disease

De: Penny Watson, Edward C Feldman, Federico Fracassi
ISBN: 9781957260747
2024, Edra
Capa dura
Páginas: 320

  • Diseases of the liver and pancreas can cause a degree of despair in veterinary practitioners: so much about the causes and treatments of these diseases is poorly understood, and too many cases remain idiopathic. Nonetheless, over recent years, clinical research makes clear that logical workup and treatment of clinical cases really can significantly impact both the quality and duration of life. There are very few, if any, clinical signs that are pathognomonic for liver or pancreas diseases, and the clinician must consider differential diagnoses for presenting signs.

    The first section of the Canine Hepatobiliary and Exocrine Pancreas Diseases with problem-orientated algorithms guides both first and second opinion practitioners through clinical assessments and workups, preventing oversight of potential underlying causes. The subsequent sections meticulously delve into pancreatic and liver diseases, encompassing clinical pathology, imaging, biopsy acquisition, cytology, and histology, all expertly elucidated by specialists. Loaded with informative algorithms, tables, figures, and videos, this book caters to the needs of busy veterinary practitioners.

    Once in a while, if you are lucky, you are asked to contribute to a really worthwhile project. This textbook on canine hepatobiliary and pancreatic diseases has been such a project. There has long been a need for a book dedicated solely to these diseases and aimed at the interested small animal veterinarian in both first and second opinion practice. I am honoured to have been asked to edit a textbook addressing diseases in these two organs, which have dominated my clinical and research work for nearly three decades.

    The layout of this book is, I believe, unique – inspired by the series editors Edward Feldman and Federico Fracassi, whose vision was integral to the book’s design. I thank them most sincerely for their patience and wise help during the planning of this book.

    There are very few, if any, clinical signs that are pathognomonic for liver or pancreas disease, and the clinician must consider differential diagnoses for presenting signs. The first section allows this with problem-orientated algorithms addressing the owner’s presenting concerns and physical examination findings, guiding the clinician into the appropriate workup, and ensuring that other potential causes of these signs are not forgotten. The book is then divided into a section on pancreatic diseases and a section on liver diseases. The organ sections start with a detailed consideration of clinical pathology, imaging, and biopsy acquisition, with additional chapters on the interpretation of cytology and histology in the liver section, all written by experts in their fields. This is followed by chapters on specific diseases of the pancreas and liver. There are many helpful algorithms, tables, figures, and videos, both in the printed book and ebook, aimed to make this a practical resource for the busy veterinary practitioner.

    Not only internal medicine specialists and residents but also specialist soft tissue surgeons, nutritionists, clinical pathologists, veterinary pathologists, oncologists, diagnostic imagers, an anaesthetist, a toxicologist, and a neurologist have contributed to this work – so there is a sense that having this book on your bookshelf is like having all these specialists in your clinic to consult on those difficult cases.

    The result is an up-to-date, and we hope complete, resource of pancreatic and liver diseases in dogs. Diseases of the liver and pancreas can cause a degree of despair in veterinary practitioners – so much about the causes and treatments of these diseases is poorly understood, and too many cases remain idiopathic. Nonetheless, over recent years, clinical research has started to improve our understanding, as detailed in this book, and it is clear that logical workup and treatment of our cases really can make a difference to both the quality and quantity of life. If this book results in increased enthusiasm amongst veterinarians in both first opinion and specialist practice to learn more about liver and pancreas disease in dogs, to treat their cases more carefully and positively, and to undertake more vital clinical research in this area, it will have achieved its goals.

    Enormous thanks are due to the really talented group of authors who have been kind enough to contribute to this book. You have all been wonderful to work with. I hope you have enjoyed our interactions as much as I have. You have given this book so much time and effort, and I have learned a lot from reading your work. I thank you all most sincerely. In addition, this would not have been possible if it were not for the extraordinary work and passion of the team from Edra and, in particular, Costanza Smeraldi, whose enthusiasm, wise and patient guidance, and hard work have made this the smoothest, most efficient, and high-quality process imaginable. Thank you all!

  • SECTION I DIFFERENTIAL DIAGNOSES FOR OWNER CHIEF CONCERNS AND PHYSICAL EXAMINATION FINDINGS

    Chapter 1 Vomiting

    Melanie Werner

    Chapter 2 Diarrhea

    Melanie Werner

    Chapter 3 Weight loss

    Mellora Sharman, Marina Martín-Ambrosio

    Chapter 4 Poor appetite/no appetite

    Sofia Rapastella, Mellora Sharman

    Chapter 5 Polyphagia

    Beatrice Ruggerone, Fabio Procoli

    Chapter 6 Polyuria/polydipsia

    Beatrice Ruggerone, Fabio Procoli

    Chapter 7 Lethargy/stupor/pacing

    Susana Monforte

    Chapter 8 Jaundice 33

    Frederik Allan

    Chapter 9 Dark feces or melena

    Floris Dröes

    Chapter 10 Abdominal enlargement

    Giulia Cattaneo

    Chapter 11 Cranial abdominal pain

    Giulia Cattaneo

    Chapter 12 Petechiae and ecchymoses

    Floris Dröes

    SECTION II DIAGNOSIS OF EXOCRINE PANCREATIC DISEASE

    Chapter 13 Nonspecific laboratory findings in pancreatic disease

    Yvonne McGrotty

    Chapter 14 More specific laboratory tests for exocrine pancreatic disease

    Harry Cridge

    Chapter 15 Pancreatic imaging

    Angela Marolf

    Chapter 16 Pancreatic biopsy

    Laura J. Owen

    SECTION III DISEASES OF THE EXOCRINE PANCREAS

    Chapter 17 Introduction to the anatomy and physiology of the exocrine pancreas

    Ran Nivy, Asaf Berkowitz

    Chapter 18 Acute pancreatitis

    Sue Yee Lim, Jörg M. Steiner

    Chapter 19 Chronic pancreatitis

    Panagiotis G. Xenoulis, Jörg M. Steiner

    Chapter 20 Exocrine pancreatic insufficiency

    Daniel Batchelor

    Chapter 21 Neoplasia of the exocrine pancreas in dogs

    Antonio Giuliano, Jane Dobson

    Chapter 22 Nutrition for acute and chronic pancreatitis and exocrine pancreatic insufficiency

    Daniel L. Chan

    Chapter 23 Analgesia in acute and chronic pancreatitis

    Ian Self

    SECTION IV Diagnosis of hepatobiliary disease

    Chapter 24 Nonspecific laboratory tests in hepatobiliary disease

    Cassia Hare

    Chapter 25 Laboratory tests more specific for hepatobiliary disease

    Alice Tamborini

    Chapter 26 Imaging the liver, biliary system, and portal vasculature

    Abby Caine

    Chapter 27 Liver biopsy

    Laura J. Owen

    Chapter 28 Interpretation of cytological examination of the liver

    Carlo Masserdotti

    Chapter 29 Interpretation of liver biopsy reports

    Sean McDonough

    SECTION V DISEASES OF THE LIVER, GALLBLADDER, AND BILIARY TRACT

    Chapter 30 Introduction to the liver anatomy and physiology

    Francesco Lotti

    Chapter 31 Acute toxic hepatopathy

    Karyn Bischoff

    Chapter 32 Acute infectious liver disease and hepatic abscess

    Katie Elizabeth McCallum

    Chapter 33 Chronic hepatitis: copper-associated

    Rommaneeya Leela-arporn, Cynthia RL Webster

    Chapter 34 Chronic hepatitis: idiopathic, autoimmune, and other non-copper-associated causes

    Adam G. Gow

    Chapter 35 Gallbladder and biliary tract diseases: mucoceles, biliary tract, and gallbladder infections

    Ben Harris

    Chapter 36 Congenital vascular diseases

    Michael S. Tivers

    Chapter 37 Other congenital liver diseases: ductal plate and gallbladder disorders

    Andre J. Kortum

    Chapter 38 Canine vacuolar hepatopathies, hepatocutaneous syndrome, and amyloidosis

    Sharon Kuzi

    Chapter 39 Liver tumors in dogs

    Luca Schiavo, Jane M. Dobson

    Chapter 40 Nutrition for acute and chronic liver disease

    Becca Leung

  • Penny Watson, MA VetMD CertVR DSAM DipECVIM MRCVS

    Senior Lecturer in Small Animal Medicine and Clinical Nutrition
    Penny graduated from Cambridge in 1989 and after spending 4 years in mixed first opinion practice, she returned to the medicine department and has stayed ever since. She has RCVS and ECVIM Diplomas in small animal medicine and is an RCVS and European recognized specialist in Small Animal Internal Medicine. She also has a doctorate on chronic pancreatitis in dogs. She is interested in all areas of small animal internal medicine, with particular focus on chronic liver disease in dogs and cats and chronic pancreatitis in dogs.

    Penny’s current research is focused on chronic pancreatitis in dogs, investigating potential mechanisms of disease in cavalier king Charles spaniels and English cocker spaniels. She is also actively investigating chronic hepatitis in dogs, particularly English Springer Spaniels and other breeds. She is always interested in hearing from referring vets about cases of chronic hepatitis or chronic pancreatitis in any breed of dog. Please visit Penny’s research profile for further information.

    Edward C. Feldman, DVM, DACVIM,

    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA;

    Prof. Frederico Fracassi

    Main field of research is the canine and feline clinical endocrinology. He holds the title of EBVS® European Veterinary Specialist in Small Animal Internal Medicine (ECVIM-CA). He is the author of more than 100 international scientific articles. He is the author of scientific textbooks translated into several languages. He is the editor of the scientific journal Veterinaria. Invited speaker at conferences or courses in more than 22 countries. At the Department of Veterinary Medical Sciences, he is the delegate for the "third mission". He is a member of the working group Section IV Consiglio Superiore di Sanità “Scientific, regulatory and operational aspects related to veterinary medicine.” He is the director of the international II level master's degree “Canine and Feline Endocrinology.”

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