• First comprehensive volume focused exclusively on the topic of cognitive dysfunction syndrome in dogs and cats

    Discusses state-of-the-art therapeutic and diagnostic approaches through the brain pathophysiology to current proteomic procedures used in this field

    Case studies linked with current scientific knowledge.

    The book deeply focuses on the epidemiology, diagnostics, therapy and molecular basis of canine and feline dementia or cognitive dysfunction syndrome. The aim is to provide a broad overview of the current knowledge on canine and feline dementia. Experiences of clinicians are appropriately linked with current scientific knowledge in a readily comprehensible form. In the first three chapters we describe the clinical pictures of canine and feline dementia, discuss the medical causes of the disease and its phenotypic variability. In the 4th chapter we introduce the dog as an appropriate animal model for human Alzheimer’s disease progression. Then we shed light on the neuropathological hallmarks of canine and feline dementia. For the first time we touch upon the modern diagnostic approaches based on the neuroproteomic technological progress. Last but not least, we address the current pharmacological and non-pharmacological approaches for therapy and risk and protective factors of feline and canine dementia. The book addresses clinicians, researchers, university teachers and graduate students in veterinary neurology and medicine.

    • Clinical Picture of Canine and Feline Cognitive Impairment

    Pages 1-12

    Landsberg, Gary M. (et al.)

    • Behavioural and Medical Differentials of Cognitive Decline and Dementia in Dogs and Cats

    Pages 13-58

    Denenberg, Sagi (et al.)

    • Phenotypic Variability and Clinical Staging of Canine Dementia

    Pages 59-68

    Mad’ari, Aladár (et al.)

    • The Aged Dog as a Natural Model of Alzheimer’s Disease Progression

    Pages 69-92

    Araujo, Joseph A. (et al.)

    • Brain Aging in the Dog

    Pages 93-102

    Nichol, Jeff (et al.)

    • Neuropathology of Feline Dementia

    Pages 103-111

    Head, Elizabeth (et al.)

    • Proteomic Approaches for Diagnostics of Canine and Feline Dementia

    Pages 113-127

    Kovacech, Branislav (et al.)

    • Current Pharmacological and Non-pharmacological Approaches for Therapy of Feline and Canine Dementia

    Pages 129-143

    Denenberg, Sagi (et al.)

    • Preventive and Risk Factors of Canine Dementia

    Pages 145-154

    Mad’ari, Aladár (et al.)

  • Dr. Gary Landsberg BSc, DVM, DACVB, dip ECAWBM received his DVM from the Ontario Veterinary College in 1976. He is a board certified veterinary behaviourist with specialist credentialing from the American College of Veterinary Behaviorists and the European College of Animal Welfare and Behavioural Medicine. He offers behavior consultation services at the North Toronto Veterinary Behaviour Specialty Clinic in Thornhill, is a consultant for VIN, Vice President of Veterinary Affairs for CanCog Technologies and a member of the Fear Free initiative executive committee. He is co-author of Behavior Problems of the Dog and Cat. Dr. Landsberg received the companion animal behavior award from AAHA in 2000 and the meritorious service award from the Western Veterinary Conference in 2014.

    Norbert Zilka is an Associate Professor at the University of Veterinary Medicine and Pharmacy in Kosice, Slovakia. He received his Ph.D. degree in immunology from the Institute of Neuroimmunology, Slovak Academy of Sciences in 2006. He is a founder and the director of the Institute of Neuroimmunology, n.o. and vice-chairperson of Slovak Society forNeuroscience. This year, he has been awarded the Doctor of Science (DSc) degree in neuroscience. He has published almost 50 original papers and reviews. His main scientific interest is on pathological hallmarks of Alzheimer’s disease and canine dementia.

    Aladar Madari is an asistent of professor at the University of veterinary medicine and pharmacy in Košice, Slovakia. He works as clinical researcher at Department of Internal Diseases in Small Animal Clinic. He received his Ph.D. degree in the internal medicine of small animals from the Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Košice, Slovakia in 2012. He specialises in neurological disease in geriatric dogs and cats in relation to behavioral changes. He developed CADES (CAnine DEmentia Scale) for quick detection of behavioral changes in senior dogs. He is one of the pioneers of behavioral medicine for small animals in Slovakia. He is a member of several professional and science societies and the Chamber of Veterinary Surgeons in Slovakia. His main professional and scientific interest is on behavioural and neuropathological changes in canine and feline neurodegenerative disorders.

Veterinary Clinics of North America
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