• This book is contemporary, topical and global in its approach, and provides an essential, comprehensive treatise on bovine tuberculosis and the bacterium that causes it, Mycobacterium bovis. Bovine tuberculosis remains a major cause of economic loss in cattle industries worldwide, exacerbated in some countries by the presence of a substantial wildlife reservoir. It is a major zoonosis, causing human infection through consumption of unpasteurised milk or by close contact with infected animals.

    Following a systematic approach, expert international authors cover epidemiology and the global situation; microbial virulence and pathogenesis; host responses to the pathogen; and diagnosis and control of the disease.

    Aimed at researchers and practising veterinarians, this book is essential for those needing comprehensive information on the pathogen and disease, and offers a summary of key information learned from human tuberculosis research. It will be useful to those studying the infection and for those responsible for controlling the disease.

    • 1: Bovine Tuberculosis: Worldwide Picture
    • 2: Mycobacterium bovis as the Causal Agent of Human Tuberculosis: Public Health Implications
    • 3: Economics of Bovine Tuberculosis: A One Health Issue
    • 4: The Epidemiology of Mycobacterium bovis Infection in Cattle
    • 5: Mycobacterium bovis Molecular Typing and Surveillance
    • 6: Bovine Tuberculosis in Other Domestic Species
    • 7: Role of Wildlife in the Epidemiology of Mycobacterium bovis
    • 8: Molecular Virulence Mechanisms of Mycobacterium bovis
    • 9: The Pathology and Pathogenesis of Mycobacterium bovis Infection
    • 10: Innate Immune Response in Bovine Tuberculosis
    • 11: Adaptive Immunity
    • 12: Immunological Diagnosis
    • 13: Biomarkers in the Diagnosis of Mycobacterium tuberculosis Complex Infections
    • 14: Vaccination of Domestic and Wild Animals Against Tuberculosis
    • 15: Managing Bovine Tuberculosis: Successes and Issues
    • 16: Perspectives on Global Bovine Tuberculosis Control

  • Mark Chambers, Animal and Plant Health Agency, UK and University of Surrey, UK,

    Stephen Gordon, University College Dublin, Ireland,

    Francisco Olea-Popelka, Western University, Canada,

    Paul Barrow, University of Surrey, UK

Veterinary Clinics of North America
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