• “This is an excellent update on the new discoveries in the field of immunology that have increased the understanding of the pathogenesis of allergic diseases.” (Doody’s, 16 January 2015)

    “These features make this a useful reference for veterinarians with an interest in veterinary allergy.” (Journal of the American Veterinary Medical Association, 15 September 2014)

    “I enjoyed this book, learned and was reminded of a lot, and I recommend it as essential reading for all veterinary dermatologists and residents. The book is good value and a good choice for practices with a library. It is available in print and electronically.” (Veterinary Record, 29 November 2014)

    “A must for anyone wishing to understand and manage accordingly those itchy, diarrhoeic or suffocating animals.” (Vets Today, 1 August 2014)

    “In this context, one sees the importance of books of this nature. As is the case with other specialized titles in veterinary medicine, I hope that Veterinary Allergy has come to stay and we will have successive revised, expanded and updated editions, helping to keep us informed and to manage our allergic patients properly.”(Veterinary Dermatology, 5 July 2014)

    “From clinical presentation and treatment to allergic diseases, science and references for specialists and researchers, and chapters written by experts, this provides a powerful and highly recommended veterinary exploration that any clinician or vet student must have in their reference collections.” (Midwest Book Review, 1 June 2014

  • Acknowledgments viii

    Contributors ix

    Foreword xiii
    Richard E.W. Halliwell

    Introduction: the immunological basis of allergic diseases xv
    Michael J. Day

    Part 1 – Canine Allergy (Editor: Chiara Noli) 1

    Section 1 – Canine Atopic Dermatitis 3

    1 Introduction: canine atopic dermatitis as an evolving, multifactorial disease 5
    Douglas J. DeBoer

    2 Canine immunoglobulin E 8
    Bruce Hammerberg

    3 The aberrant immune system in atopic dermatitis 16
    Rosanna Marsella

    4 Allergens and environmental influence 24
    Pascal Prélaud

    5 The genetics of canine atopic dermatitis 32
    Tim Nuttall

    6 Skin barrier and its role in the pathophysiology of atopic dermatitis 42
    Koji Nishifuji

    7 The role of bacterial agents in the pathogenesis of canine atopic dermatitis 51
    David H. Lloyd

    8 The role of fungal agents in atopic dermatitis 58
    Ross Bond

    9 Clinical signs of canine atopic dermatitis 65
    Claude Favrot

    10 Diagnosis of canine atopic dermatitis 70
    Craig E. Griffin

    11 Allergen avoidance 78
    Daniel O. Morris

    12 Allergen-specific immunotherapy 85
    Ralf S. Mueller

    13 Guidelines for symptomatic medical treatment of canine atopic dermatitis 90
    Douglas J. DeBoer

    14 Non-conventional treatments 96
    Ralf S. Mueller

    Section 2 – Food Hypersensitivity 101

    15 The pathogenesis of food allergy 103
    Hilary A. Jackson

    16 Cutaneous manifestations of food hypersensitivity 108
    Didier N. Carlotti

    17 Adverse reactions to food: a gastroenterologist’s perspective 115
    Paola Gianella

    18 Diagnostic workup of food hypersensitivity 119
    Edmund J. Rosser Jr

    19 Long-term management of food hypersensitivity in the dog 124
    Nick J. Cave

    Section 3 – Flea Bite Allergy 133

    20 Flea biology and ecology 135
    Marie-Christine Cadiergues

    21 The pathogenesis of flea bite allergy in dogs 140
    Richard E.W. Halliwell

    22 Clinical signs of flea allergy dermatitis in dogs 145
    Emmanuel Bensignor

    23 Diagnostic investigation of canine flea bite allergy 149
    Dawn Logas

    24 Implementing an effective flea control programme 152
    Michael W. Dryden

    25 Symptomatic relief for canine flea bite hypersensitivity 158
    Dawn Logas

    Section 4 – Complicating Infections in Allergic Dogs 161

    26 Complicating microbial skin infections in allergic dogs 163
    Anette Loeffler

    27 Otitis in the allergic dog 175
    James O. Noxon

    Section 5 – Other Allergic Diseases in Dogs 183

    28 Contact allergy 185
    Rosanna Marsella

    29 Venomous insect hypersensitivity 191
    Mona J. Boord

    30 Canine urticaria and angioedema 195
    Peter Hill

    Part 2 – Feline Allergy (Editor: Aiden Foster) 201

    Section 1 – Cutaneous Allergy in Cats 203

    31 Pathogenesis—immunopathogenesis 205
    Petra J. Roosje

    32 Clinical presentations and specificity of feline manifestations of cutaneous allergies 211
    Claude Favrot

    33 Complications of cutaneous skin allergies (skin infections) 217
    Laura Ordeix

    34 Diagnostic investigation of the allergic feline 223
    William E. Oldenhoff and Karen A. Moriello

    35 Symptomatic treatments 228
    Alison B. Diesel

    36 Allergen-specific immunotherapy 234
    Alison B. Diesel

    Section 2 – Feline Asthma 237

    37 Feline asthma 239
    Carol R. Reinero

    Section 3 – Flea Bite Allergy 247

    38 Pathogenesis 249
    Ross Bond

    39 Clinical presentations 252
    Dawn Logas

    40 Diagnostic workup 255
    Dawn Logas

    41 Therapy 259
    Marie-Christine Cadiergues

    Section 4 – Mosquito Bite Allergy 265

    42 Mosquito bite 267
    Masahiko Nagata

    Part 3 – Equine Allergy (Editor: Wayne Rosenkrantz) 271

    Section 1 – Culicoides Hypersensitivity and Other Insect Allergies 273

    43 Pathogenesis and epidemiology of Culicoides hypersensitivity 275
    Bettina Wagner

    44 Equine immunoglobulin E 279
    Eliane Marti and Eman Hamza

    45 Clinical manifestations of Culicoides hypersensitivity 287
    Janet D. Littlewood

    46 Culicoides hypersensitivity: diagnosis 291
    Kerstin Bergvall

    47 Culicoides hypersensitivity: therapy 297
    Anthony A. Yu

    48 Other biting insect allergies 307
    Gwendolen Lorch

    Section 2 – Atopic Disease in Horses—Atopic Dermatitis and Food Hypersensitivity 327

    49 Equine atopic dermatitis: pathogenesis 329
    Valerie A. Fadok

    50 Clinical aspects of equine atopic disease 334
    Wayne Rosenkrantz and Stephen White

    51 Equine urticaria 338
    Valerie A. Fadok

    52 Equine headshaking syndrome 344
    Harold C. Schott II and Annette D. Petersen

    53 Diagnostic workup of equine atopic disease 353
    Wayne Rosenkrantz and Stephen White

    54 Equine atopic disease symptomatic therapy and allergen-specific immunotherapy 360
    Wayne Rosenkrantz and Stephen White

    Section 3 – Recurrent Airway Obstruction and Inflammatory Airway Disease 371

    55 Recurrent airway obstruction and inflammatory airway disease 373
    Vinzenz Gerber

    Section 4 – Contact and Other Allergic Diseases 385

    56 Equine allergic contact dermatitis 387
    Chris Reeder and Joya Griffin

    Part 4 – Allergy in Other Domestic Species (Editor: Aiden Foster) 395

    57 Immunopathogenesis of allergic skin disease in livestock 397
    Adri van den Broek

    58 Psoroptes ovis 402
    Adri van den Broek and Stewart T.G. Burgess

    59 Allergic diseases of livestock species 411
    Aiden P. Foster

    60 Allergies in birds 422
    Claudia S. Nett-Mettler

    61 Allergic diseases in other pets (rodents, rabbits, and ferrets) 428
    Ian Sayers

    Index 433

  • Chiara Noli, DVM, DipECVD
    Dr. Chiara Noli graduated in veterinary medicine from the University of Milan, Italy, in 1990. After a residency at the University of Utrecht, Holland, she obtained the European Diploma in Veterinary Dermatology in 1996. Since then she works as referral dermatologist and dermatopathologist in Northen Italy. Dr. Noli is Past President and Founder Member of the Italian Society of Veterinary Dermatology, Past President of the European Society of Veterinary Dermatology and has been Board Member of the International Society of Veterinary Dermatopathology and of the World Association for Veterinary Dermatology. Dr. Noli lectures extensively in national and international meetings, is author of more than 100 articles in Italian and international journals, of nine book chapters and of three veterinary dermatology textbooks.

    Aiden Foster PhD, DipACVD, MRCVS
    Aiden Foster worked for 20 years dealing with companion animal dermatology cases in referral and first opinion practices. He trained in veterinary dermatology at the College of Veterinary Medicine, University of Wisconsin, USA and taught veterinary dermatology at the University of Bristol veterinary school. He has been the editor of the BSAVA Manual of Small Animal Dermatology 2nd edition and was an editor of the proceedings of the 5th World Congress of Veterinary Dermatology published as Advances in Veterinary Dermatology volume 5. He is a past president of the European Society of Veterinary Dermatology and has been editor-in-chief of the Wiley-Blackwell journal Veterinary Dermatology since 2006. He works for the Animal Health and Veterinary Laboratories Agency which deals with diseases of livestock.

    Wayne Rosenkrantz DVM, DipACVD
    Wayne Rosenkrantz graduated from the University of California Davis in 1982. He obtained Diplomate status with the American College of Veterinary Dermatology (ACVD) in 1986. Dr. Rosenkrantz is a co-owner of all of the Animal Dermatology Clinics in the United States, and continues to actively see cases. He is a past-president of the American College of Veterinary Dermatology (ACVD) executive board and has been on past and current organizing committees for the World Congress of Veterinary Dermatology (WCVD) and a current member of the World Association for Veterinary Dermatology (WAVD). He has served on the examination committees for the ACVD as well as the Australian Board examinations. Dr. Rosenkrantz lectures and teaches extensively, and has published numerous articles and book chapters on small animal and equine dermatology. He is very active in clinical drug trials, research studies and consults with several dermatological therapeutic companies. He also received the ACVD Award for Excellence for outstanding contributions in veterinary dermatology in 2007.

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