• A comprehensive image-based reference to all aspects of small animal cytology and hematology, including sample collection and handling

    Clinical Atlas of Small Animal Cytology and Hematology, Second Edition is an essential, comprehensive resource for all veterinary professionals preparing and evaluating cytology and blood samples. Featuring hundreds of large, high-quality images, this fully updated new edition provides an even more extensive collection of exceptional photomicrographs, accompanied by detailed descriptions, figure legends and annotations to guide readers through the diagnostic process.

    The Second Edition adds an extensive new hematology section, new chapters detailing sample acquisition and preparation, and many new diseases across all chapters. Each section provides a detailed description of the microscopic appearance, clinical considerations, and prognosis for each disease, using a bullet point format to promote rapid review for efficient, evidence-based clinical decision making.

    Clinical Atlas of Small Animal Cytology and Hematology features:

    • More than 750 high-quality cytology and hematology images
    • 6 new chapters, including detailed sections on sample acquisition and the preparation and staining of cytology and hematology slides
    • A comprehensive hematology section including an easy-to-follow blood smear interpretation guide, and detailed chapters describing erythrocytes, leukocytes, platelets and background features.
    • Updated cytology sections with new diseases and images in all chapters

    Easy to use, with superior quality images and detailed yet succinct clinical information, Clinical Atlas of Small Animal Cytology and Hematology is a powerful resource to help improve confidence and skill in the interpretation of cytology and hematology samples, and in turn positively impact patient care and outcomes.

  • Preface


    1 Cytology Sampling and Preparation

    1.1 Cytology

    1.2 Sample Collection and Preparation

    1.3 Sample Staining

    1.4 Sample Handling and Storage


    2 Cytologic Analysis of Cells

    2.1 Approach to Cytology Samples

    2.2 Sample Quality and Background

    2.3 Cell Types

    2.4 Cell Shape, Distribution, and Features

    2.5 Benign Versus Malignant


    3 Infectious Agents

    3.1 Fungi

    3.2 Oomycetes

    3.3 Algae

    3.4 Mesomycetozoea

    3.5 Protozoa

    3.6 Helminths

    3.7 Bacteria

    3.8 Ectoparasites


    4 Integument

    4.1 Cutaneous and Subcutaneous Lesions


    5 Hemolymphatic

    5.1 Lymph Nodes

    5.2 Spleen

    5.3 Thymus

    5.4 Bone Marrow


    6 Body Cavity Fluids

    6.1 General Classification

    6.2 Specific Effusions


    7 Musculoskeletal

    7.1 Bone

    7.2 Joints

    7.3 Muscle


    8 Hepatobiliary

    8.1 Liver

    8.2 Biliary Tract


    9 Digestive System

    9.1 Salivary Glands

    9.2 Stomach/Intestines

    9.3 Feces

    9.4 Pancreas


    10 Urinary

    10.1 Kidney

    10.2 Bladder

    10.3 Urine

    10.4 Urinary Crystals

    10.5 Urinary Casts


    11 Respiratory

    11.1 Nasal Cavity

    11.2 Lung

    11.3 Bronchoalveolar Lavage (BAL)/Transtracheal Wash (TTW)


    12 Endocrine

    12.1 Thyroid

    12.2 Parathyroid

    12.3 Chemoreceptor Tumors

    12.4 Adrenal Gland

    12.5 Pituitary Gland


    13 Reproductive


    13.1 Testes

    13.2 Semen Analysis

    13.3 Prostate

    13.4 Penis


    13.5 Ovary

    13.6 Mammary Glands

    13.7 Vaginal Cytology


    14 Neurologic

    14.1 Brain

    14.2 Cerebrospinal Fluid (CSF)

    14.3 Spinal Cord


    15 Ocular and Special Senses

    14.1 Eyes: Cornea

    14.2 Eyes: Conjunctiva

    14.3 Ears


    16 Blood Smear Preparation and Evaluation

    16.1 The Importance of Blood Smear Evaluation

    16.2 Making a Blood Smear

    16.3 Blood Smear Staining and Handling

    16.4 Blood Smear Evaluation

    16.5 Hematology Procedures and Techniques


    17 Erythrocytes

    17.1 Approach to Evaluating Red Blood Cells

    17.2 Red Blood Cell Distribution

    17.3 Red Blood Cell Morphology

    17.4 Red Blood Cell Inclusions

    17.5 Red Blood Cell Neoplasia

    17.6 Red Blood Cell Infectious Agents


    18 Leukocytes

    18.1 Approach to Evaluating Leukocytes

    18.2 Neutrophils

    18.3 Neutrophil Inclusions

    18.4 Eosinophils

    18.5 Basophils

    18.6 Mast Cells

    18.7 Monocytes

    18.8 Lymphocytes

    18.9 Leukocyte Neoplasia

    18.10 Leukocyte Infectious Agents


    19 Platelets

    19.1 Approach to Evaluating Platelets

    19.2 Platelet Distribution

    19.3 Platelet Morphology

    19.4 Platelet Neoplasia

    19.5 Platelet Infectious Agents


    20 Background Features and Miscellaneous Cells

    20.1 Approach to Blood Smear Background Features

    20.2 Acellular Elements

    20.3 Miscellaneous Cells

    20.4 Infectious Agents



  • Andrew G. Burton, BVSc, DACVP

    Is a Clinical Pathologist at IDEXX Laboratories, North Grafton, Massachusetts, USA.